Article

Quercetin and a plant substance, identified using a multi-copy number of DNA topoisomerase I in recombinant Pichia pastoris, inhibited MDA-MB-231 proliferation via different manners.

2021-04-30

Abstract excerpt

<title>Abstract</title> <p>The study employed an <italic>in vivo</italic> strategy to construct a multi-copy number of human DNA topoisomerase I (hTopI) gene using pPIC3.5K vector in GS115 strain of <italic>Pichia</italic>. The yeast transformant (GS115-pPIC3.5K-hTopI; clone) was then used to investigate the preliminary growth effect of a pure compound (quercetin) and a standardised subfraction of ethanolic red o...

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Literature Corpus work: 91e5411d-0b26-5a44-9f5b-346ced5201e6
DOI: 10.21203/rs.3.rs-341312/v2

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Quercetin and a plant substance, identified using a multi-copy number of DNA topoisomerase I in recombinant Pichia pastoris, inhibited MDA-MB-231 proliferation via different manners.DOI 10.21203/rs.3.rs-341312/v2Read

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