Article

Cryo-EM structure of ex vivo Sup35 yeast prion and the factors defining prion phenotype

2026-02-03

Abstract excerpt

<title>Abstract</title> <p> Human prions and amyloids exhibit structural diversity that correlates with different pathology manifestations. Yeast prions represent a convenient model for studying basic properties of prions and their strain diversity. The yeast Sup35 prion has multiple structural variants divided into two groups, “strong” and “weak”, differing in the frequency of fibril fragmentation and resulting...

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Literature Corpus work: 914d9347-e499-5c43-8a60-f278fbe2135b
DOI: 10.21203/rs.3.rs-8764517/v1

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