Article

Human follicular fluid-derived exosomal microRNAs ameliorate aging-associated ovarian hypofunction through miR-671-3p–mediated targeting of PIP5K1A

2026-06-15

Abstract excerpt

<title>Abstract</title> <p>Background Specific exosome components in follicular fluid are involved in human folliculogenesis and somatic cell‒germ cell communication in the ovarian microenvironment, providing unique insights into the mechanism of infertility in aging women. Methods Follicular fluid were collected from young (n = 5) and aged (n = 5) women. Exosomes were isolated by ultracentrifugation and identi...

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Literature Corpus work: 9146b7a3-59c2-5aeb-83e1-71f3e4dcdd53
DOI: 10.21203/rs.3.rs-9771729/v1

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