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Mitochondrial dysfunction in cumulus cells is related to decreased reproductive capacity in advanced-age women

28 May 2022

Abstract excerpt

OBJECTIVE: To reveal the relationship between mitochondrial function in cumulus cells (CCs) and the aging-related decline in ovarian function and reproductive capacity. DESIGN: Retrospective and transcriptome analysis of human tissue. SETTING: University hospital. PATIENT(S): A total of 186 infertile women with normal weight and no other diseases, including 86 young women (aged <38 years) with normal ovarian...

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PMID: 35637023
DOI: 10.1016/j.fertnstert.2022.04.019

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