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Article

An investigation of GRP78 expression and inhibition in squamous cell carcinoma of the head and neck

2011-01-01

Abstract excerpt

GRP78 is a known cyto-protective gene which is induced in microenvironments typical of tumours with low glucose and hypoxia. Furthermore up-regulation of GRP78 has been linked to chemo- and radioresistance as well as poor survival outcome. This study is the first to confirm that GRP78 is up-regulated in tumours of the oropharynx, larynx and hypopharynx compared with matched histologically normal tissue (p(Χ2)<0.00...

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Identifiers and source

Literature Corpus work
91184912-3f4c-5833-95ad-2a61169954a9
DOI
10.17638/00003813
Open publication

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