Article

Upregulation of Cytoglobin in 3D-cultures of Head and Neck Cancer Cells: Role of Hypoxia and Implications for Cisplatin Resistance

2022-08-02

Abstract excerpt

Cytoglobin has been implicated in a range of pathological conditions including fibrosis and cancer, where cytoglobin expression is linked to hypoxia- and drug-resistance. One disease where there is evidence of a role for cytoglobin is head and neck squamous cell carcinoma, a disease with a poor prognosis and where clinical resistance to platinum-based drugs is common. In the current study, we demonstrate that 3D-c...

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Literature Corpus work: 123ec26c-1011-5371-8f2b-738be3e4a91d
DOI: 10.20944/preprints202208.0043.v1

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