Article

Identification of eight SARS-CoV-2 ORF7a deletion variants in 2,726 clinical specimens

2020-12-11

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ORF7a, the ortholog of SARS-CoV ORF7a, is a type I transmembrane protein and plays an important role in virus-host interactions. Deletion variants in ORF7a may influence virulence, but only a few such isolates have been reported. Here, we report 8 unique ORF7a deletion variants of 6 to 96 nucleotides in length identified from 2,726 clinical specimens col...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 90e2dc11-697f-5da5-be70-7b66e23d24bb
DOI: 10.1101/2020.12.10.418855

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of eight SARS-CoV-2 ORF7a deletion variants in 2,726 clinical specimensDOI 10.1101/2020.12.10.418855Read

Expansion of a SARS-CoV-2 Delta variant with an 872 nt deletion encompassing ORF7a, ORF7b and ORF8, Poland, July to August 2021Semantic proximity Read

Identification of multiple large deletions in ORF7a resulting in in-frame gene fusions in clinical SARS-CoV-2 isolatesSemantic proximity Read

A deletion in SARS‐CoV‐2 ORF7 identified in COVID‐19 outbreak in UruguaySemantic proximity Read

Characterization of SARS-CoV-2 ORF6 deletion variants detected in a nosocomial cluster during routine genomic surveillance, Lyon, FranceSemantic proximity Read

Detection of SARS-CoV-2 Δ426 ORF8 Deletion Mutant Cluster in NGS ScreeningSemantic proximity Read

Identification of multiple large deletions in ORF7a resulting in in-frame gene fusions in clinical SARS-CoV-2 isolatesSemantic proximity Read

Multiple Occurrences of a 168-Nucleotide Deletion in SARS-CoV-2 ORF8, Unnoticed by Standard Amplicon Sequencing and Variant Calling Pipelines.Semantic proximity Read

SARS-CoV-2 genomic surveillance identifies naturally occurring truncations of ORF7a that limit immune suppressionSemantic proximity Read

Genome Sequences of Three SARS-CoV-2 ORF7a Deletion Variants Obtained from Patients in Hong KongSemantic proximity Read

SARS-CoV-2 genomic surveillance identifies naturally occurring truncation of ORF7a that limits immune suppression.Semantic proximity Read

Characterization of SARS-CoV-2 ORF6 deletion variants detected in a nosocomial cluster during routine genomic surveillance, Lyon, France.Semantic proximity Read

Variant analysis of 1,040 SARS-CoV-2 genomes.Semantic proximity Read