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Clinical criteria for genetic testing in pediatric oncology show a low specificity and miss every 4<sup>th</sup>child carrying a cancer predisposition

2022-10-22

Abstract excerpt

Clinical checklists are the current gold standard to determine whether a child with cancer shows indications for genetic testing. Nevertheless, the efficacy of these tests to reliably detect genetic cancer predisposition in children with cancer is still insufficiently investigated. Here, we assessed the validity of clinically recognizable signs to identify cancer predisposition by correlating a state-of-the-art cl...

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Literature Corpus work
b3b8e133-6f96-55a6-990b-8d655cf12df7
DOI
10.1101/2022.10.22.22281392
Open publication

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Clinical criteria for genetic testing in pediatric oncology show a low specificity and miss every 4<sup>th</sup>child carrying a cancer predispositionDOI 10.1101/2022.10.22.22281392
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