Article

16S rRNA gene sequencing reveals site-specific signatures of the upper and lower airways of cystic fibrosis patients

2017-04-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Rationale</h4> Chronic rhinosinusitis (CRS) is an inflammatory disorder of the sinonasal mucosa associated with microbial colonization. Metastasis of sinus microbiota into the lower airways is thought have significant implications in the development of chronic respiratory disease. However, this dynamic has not been thoroughly investigated in cystic fibrosis (CF) patients, where lower airway...

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Literature Corpus work: 907063cf-2a94-50e3-b604-e2f3dd17e72c
DOI: 10.1101/125187

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