Low Diversity and Instability of the Sinus Microbiota over Time in Adults with Cystic Fibrosis

Abstract excerpt

Together with prior sinus microbiota studies of adults with CF chronic rhinosinusitis, our study underscores similarities between sinus and lower respiratory tract microbial community structures in CF. We show how community structure tracks with inflammation and several disease measures. This work strongly suggests that clinical management of CRS could be leveraged to improve overall respiratory health in CF. Our...

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