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Comparison between upper and lower airway microbiome profiles in chronic rhinosinusitis patients

11 Feb 2024

Abstract excerpt

BACKGROUND: Dysregulation of the airway microbiota is thought to contribute to airway inflammation in both chronic rhinosinusitis (CRS) and asthma. However, the relationship between the upper and lower airway microbiome remains unclear. METHODS: Sinus and lung brushes were collected from 29 CRS participants undergoing sinus surgery. DNA was extracted and submitted for 16s rRNA microbiome sequencing. Alpha and...

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PMID: 38343306
DOI: 10.1002/alr.23335

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