Article

An inability to maintain the ribonucleoprotein genomic structure is responsible for host detection of negative-sense RNA viruses

2020-03-13

Abstract excerpt

<h4>SUMMARY</h4> Cellular biology has a uniformity not shared amongst viruses. This is perhaps best exemplified by negative-sense RNA viruses that encode their genetic material as a ribonucleoprotein complex composed of genome, RNA-dependent RNA polymerase, and the nucleoprotein. Here we demonstrate that limiting nucleoprotein availability not only universally culminates in a replicative catastrophe for negative-...

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Identifiers and source

Literature Corpus work: 906bd6b0-2bdb-57c9-abc6-146368711586
DOI: 10.1101/2020.03.12.989319

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