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Negative and ambisense RNA virus ribonucleocapsids: more than protective armor

26 Sept 2023

Abstract excerpt

Negative and ambisense RNA viruses are the causative agents of important human diseases such as influenza, measles, Lassa fever, and Ebola hemorrhagic fever. The viral genome of these RNA viruses consists of one or more single-stranded RNA molecules that are encapsidated by viral nucleocapsid proteins to form a ribonucleoprotein complex (RNP). This RNP acts as protection, as a scaffold for RNA folding, and as the...

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PMID: 37750733
DOI: 10.1128/mmbr.00082-23

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