Virus DNA Replication and the Host DNA Damage Response

doi:10.1146/annurev-virology-092917-043534

Article

Virus DNA Replication and the Host DNA Damage Response

11 Jul 2018

Abstract excerpt

Viral DNA genomes have limited coding capacity and therefore harness cellular factors to facilitate replication of their genomes and generate progeny virions. Studies of viruses and how they interact with cellular processes have historically provided seminal insights into basic biology and disease mechanisms. The replicative life cycles of many DNA viruses have been shown to engage components of the host DNA...

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