Article

Deciphering Molecular Mimicry: An In Silico Exploration of Heat shock protein 70 Conservation and its Role in Cross-Reactivity.

2026-08-07

Abstract excerpt

Objectives To evaluate the sequence and structural conservation of heat shock protein 70 (HSP70) across different allergenic sources and to assess its potential role in molecular mimicry- mediated cross- reactivity . Additionally, conserved linear and conformational epitopes potentially involved in immune recognition were identified. Methods An in silico analysis was performed using HSP70 amino acid sequences fro...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 90590dd0-884d-5448-8b09-e490a2ae75f2
DOI: 10.12688/f1000research.180672.1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Deciphering Molecular Mimicry: An In Silico Exploration of Heat shock protein 70 Conservation and its Role in Cross-Reactivity.DOI 10.12688/f1000research.180672.1Read

Covid-19, heat shock proteins, and autoimmune bullous diseases: a potential link deserving further attentionSemantic proximity Read

Epitopes of Microbial and Human Heat Shock Protein 60 and Their Recognition in Myalgic EncephalomyelitisSemantic proximity Read

Visiting Molecular Mimicry Once More: Pathogenicity, Virulence, and AutoimmunitySemantic proximity Read

Bioinformatic Approach to Cross-Reactivity Between Dust Mites and Scabies Mites: Clinical and Molecular ImplicationsSemantic proximity Read

Morbid Sequences Suggest Molecular Mimicry between Microbial Peptides and Self-Antigens: A Possibility of Inciting AutoimmunitySemantic proximity Read

Facets of heat shock protein 70 show immunotherapeutic potentialSemantic proximity Read

Toward Consensus Epitopes B and T of Tropomyosin Involved in Cross-Reactivity across Diverse Allergens: An In Silico StudySemantic proximity Read

Analysis molecular mimicry between protozoa Giardia intestinalis and autoantigens implicated in autoimmune reactive arthritis: potential cross-reactivitySemantic proximity Read

Generation and Activity Evaluation of a Mouse-Human Immunoglobulin G1 Chimeric Antibody to Histoplasma capsulatum HSP60Semantic proximity Read

Data-driven large-scale genomic analysis reveals an intricate phylogenetic and functional landscape in J-domain proteinsSemantic proximity Read

<i>M. paratuberculosis</i>Heat Shock Protein 65 and Human Diseases: Bridging Infection and AutoimmunitySemantic proximity Read

Homologies between SARS-CoV-2 and allergen proteins may direct T cell-mediated heterologous immune responsesSemantic proximity Read