Article
Generation and Activity Evaluation of a Mouse-Human Immunoglobulin G1 Chimeric Antibody to Histoplasma capsulatum HSP60
2021-04-05
Abstract excerpt
Heat shock proteins (Hsps) are highly conserved molecules that are constitutively expressed and upregulated in response to physiological stress conditions. These immunogenic chaperones can have essential functions in fungi, particularly in dimorphic pathogens. Histoplasma capsulatum and Paracoccidioides species are dimorphic fungi that are the causative agents of histoplasmosis and paracoccidioidomycosis, respecti...
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Identifiers and source
- Literature Corpus work
- 56f3fa61-8909-54e5-9c5f-f7bdf443c92d
- DOI
- 10.20944/preprints202104.0101.v1
