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Homologies between SARS-CoV-2 and allergen proteins may direct T cell-mediated heterologous immune responses

26 Feb 2021

Abstract excerpt

The outbreak of the new severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a public health emergency. Asthma does not represent a risk factor for COVID-19 in several published cohorts. We hypothesized that the SARS-CoV-2 proteome contains T cell epitopes, which are potentially cross-reactive to allergen epitopes. We aimed at identifying homologous peptide sequences by means of two distinct...

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PMID: 33637823
DOI: 10.1038/s41598-021-84320-8

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