Article
Quantifying within-household tuberculosis transmission: a systematic review and prospective cohort study.
International journal of epidemiology - 18 Feb 2026
Huang Chuan-Chin, Madden Alicia E, Becerra Mercedes C, Calderon Roger, Chu Alexander L, Contreras Carmen, Jimenez Judith, Lecca Leonid, Yataco Rosa, Tan Qi, Zhang Zibiao, Jauregui Elena, Murray Megan B
Abstract excerpt
BACKGROUND: Household-based studies are commonly used to investigate tuberculosis (TB) transmission and evaluate preventive interventions. These studies typically assume that household contacts (HHCs) who develop TB disease were infected by the identified index patient. However, community-acquired infections may challenge this assumption, potentially biasing findings. Here, we evaluated the proportion of...
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