Article

Automated Plasma Phospho-tau217 Assays for the diagnosis of Down Syndrome-Related Alzheimer's Disease

2025-09-01

Abstract excerpt

<title>Abstract</title> <p>Individuals with Down syndrome (DS) develop a genetic form of Alzheimer’s disease (AD) due to an extra copy of chromosome 21, which contains the APP gene. The widespread implementation of blood-based biomarkers for AD is imminent. These tests hold promise for diagnosing AD in DS once validated. In this study, we assessed plasma phospho-tau217 (p-tau217) in participants from the NIH Tria...

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Literature Corpus work: 9027c240-445f-5925-a13b-2866b53640e0
DOI: 10.21203/rs.3.rs-7359108/v1

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