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Increased levels of plasma total tau in adult Down syndrome

30 Nov 2017

Abstract excerpt

Down syndrome (DS) is the most prevalent chromosomal abnormality. Early-onset dementia with the pathology of Alzheimer's disease (AD) frequently develops in DS. Reliable blood biomarkers are needed to support the diagnosis for dementia in DS, since positron emission tomography or cerebrospinal fluid sampling is burdensome, particularly for patients with DS. Plasma t-tau is one of the established biomarkers for...

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PMID: 29190730
DOI: 10.1371/journal.pone.0188802

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