Article

Peripheral tolerance to insulin is encoded by mimicry in the microbiome

2019-12-19

Abstract excerpt

How organisms achieve sustained peripheral tolerance throughout their lifetime, a correct immune discrimination between self and non-self, remains poorly understood. Host-microbiome interactions carry fundamental information that facilitates this process. We hypothesize that commensal microbes are under evolutionary pressure to develop epitopes that, when presented along with other antigens from their own bacteria...

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Identifiers and source

Literature Corpus work: 8ff69a2a-b116-5a67-86bc-dbe1a44d8503
DOI: 10.1101/2019.12.18.881433

Open publication

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