Article

Stochastic model of contact inhibition and the proliferation of melanoma <i>in situ</i>

2017-02-20

Abstract excerpt

<h4>ABSTRACT</h4> Contact inhibition is a central feature orchestrating cell proliferation in culture experiments; its loss is associated with malignant transformation and tumorigenesis. We performed a co-culture experiment with human metastatic melanoma cell line (SKMEL-147) and immortalized keratinocyte cells (HaCaT). After 8 days a spatial pattern was detected, characterized by the formation of clusters of mel...

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Literature Corpus work: 8fcb16aa-3f19-54b3-909a-37b5abb7486c
DOI: 10.1101/110007

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