Article

Identification of stromal genes differentially expressed in lobular breast cancer highlights role for pregnancy-associated-plasma protein-A

2020-04-25

Abstract excerpt

<h4>Background</h4> Invasive lobular carcinoma (ILC) is the second most common histological subtype of breast cancer and exhibits a number of clinico-pathological characteristics that are distinct from the more common invasive ductal carcinoma (IDC). Despite these differences, ILC is treated in the same way as IDC. We set out to identify alterations in the tumor microenvironment (TME) of ILC with potential clinic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8fb3aed0-ede6-5a21-82fc-3905a7f6ef34
DOI: 10.1101/2020.04.24.059386

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of stromal genes differentially expressed in lobular breast cancer highlights role for pregnancy-associated-plasma protein-ADOI 10.1101/2020.04.24.059386Read

Stromal Transcriptome Analysis of Human Lobular Breast Cancer Identifies a Role for Pregnancy-Associated-Plasma Protein-ASemantic proximity Read

The molecular underpinning of lobular histological growth pattern: a genome‐wide transcriptomic analysis of invasive lobular carcinomas and grade‐ and molecular subtype‐matched invasive ductal carcinomas of no special typeSemantic proximity Read

Gene expression profiling of the tumor microenvironment during breast cancer progressionSemantic proximity Read

Proteomic Analysis of Breast Cancer Subtypes Identifies Stromal Protein Profiles that Contribute to Aggressive Malignant BehaviorSemantic proximity Read

High‐throughput proteomics of breast cancer interstitial fluid: identification of tumor subtype‐specific serologically relevant biomarkersSemantic proximity Read

Molecular signatures suggest a major role for stromal cells in development of invasive breast cancer.Semantic proximity Read

Why the stroma matters in breast cancer: insights into breast cancer patient outcomes through the examination of stromal biomarkers.Semantic proximity Read

Differential Analysis of Stromal-Epithelial Interactions between In Situ and Invasive Breast Cancer using Gene Expression ProfilingSemantic proximity Read

Different Gene Expression Patterns in Invasive Lobular and Ductal Carcinomas of the BreastSemantic proximity Read

Gene Expression Profiling of Fibroepithelial Lesions of the BreastSemantic proximity Read

Premenopausal women with breast cancer in the early postpartum period show molecular profiles of invasion and are associated with poor prognosisSemantic proximity Read

Characterization of the tumor immune microenvironment in pregnancy-associated breast cancer through multiplex immunohistochemistry and transcriptome analysesSemantic proximity Read