Article

Caveolae and Bin1 form ring-shaped platforms for T-tubule initiation

2022-11-03

Abstract excerpt

<h4>ABSTRACT</h4> Excitation-contraction coupling requires a highly specialized membrane structure, the triad, composed of a plasma membrane invagination, the T-tubule, surrounded by two sarcoplasmic reticulum terminal cisternae. Although the precise mechanisms governing T-tubule biogenesis and triad formation remain largely unknown, studies have shown that caveolae participate in T-tubule formation and mutations...

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Literature Corpus work: f9dfb165-8c9b-5368-ba1c-eb3d6cd71ced
DOI: 10.1101/2022.11.01.514746

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