Article

A Non-Invasive Urinary Bile-Acid Marker for Never-Smoker Lung Cancer

2026-07-31

Abstract excerpt

<h4>Introduction</h4> Lung cancer in never-smokers is a growing, biologically distinct entity lacking non-invasive markers. Established urinary markers—creatine riboside (CR) and N-acetylneuraminic acid (NANA)—report tumor-intrinsic metabolism, not carcinogen processing. We investigated 27-nor-5β-cholestane-3α,7α,12α,24R,25S-pentol glucuronide (CPG), a bile-acid glucuronide linked to aryl-hydrocarbon-receptor (Ah...

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Literature Corpus work: 8f69967d-af2a-57ad-9722-ce5e2cf2f6ca
DOI: 10.64898/2026.07.27.26359037

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