Article

Mutational Constraint Analysis Workflow for Overlapping Short Open Reading Frames and Genomic Neighbours

2024-07-10

Abstract excerpt

Understanding the dark genome is a priority task following the complete sequencing of the human genome. Short open reading frames (sORFs) are a group of largely unexplored elements of the dark genome with the potential for being translated into microproteins. The definitive number of coding and regulatory sORFs is not known, however they could account for up to 1-2% of the human genome. This corresponds to an orde...

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Literature Corpus work: 8f695d2e-bcf6-549a-9e63-4fea96305755
DOI: 10.1101/2024.07.07.602395

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