Article
Biomarkers in toxicology and risk assessment: informing critical dose-response relationships.
Chemical research in toxicology - 1 Jan 2008
Swenberg James A, Fryar-Tita Elizabeth, Jeong Yo-Chan, Boysen Gunnar, Starr Thomas, Walker Vernon E, Albertini Richard J
Abstract excerpt
Tremendous advances have been made in the study of biomarkers related to carcinogenesis during the past 20 years. This perspective will briefly review improvements in methodology and instrumentation that have increased our abilities to measure the formation, repair, and consequences of DNA adducts. These biomarkers of exposure, along with surrogates such as protein adducts, have greatly improved our understanding...
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