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A remarkable expansion of secreted cysteine knot proteins reveals novel virulence factors in the human fungal pathogen <i>Histoplasma</i>

2025-05-13

Abstract excerpt

Identifying fungal secreted factors that influence host infection remains a key challenge in microbial pathogenesis. While secreted effectors, particularly small cysteine-rich proteins, are well characterized in plant fungal pathogens, their counterparts in mammalian pathogens remain elusive. We applied criteria from plant fungal effectors to the mammalian fungal pathogen Histoplasma , yielding a set of putative...

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Literature Corpus work
8f590538-c402-506f-82b0-feef72c8eb09
DOI
10.1101/2025.05.13.653811
Open publication

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A remarkable expansion of secreted cysteine knot proteins reveals novel virulence factors in the human fungal pathogen <i>Histoplasma</i>DOI 10.1101/2025.05.13.653811
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