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miR-100-5p Enhanced Cell Cycle-mediated Chemoresistance Through Modulating CTDSPL/pRB/E2F1 Signaling Pathway in Oxaliplatin-Resistant Colorectal Cancer

2022-02-25

Abstract excerpt

<h4>Purpose: </h4> miR-100-5p has been found upregulated in Oxaliplatin-resistant LoVo colorectal cell lines, but its function still need further study. Here, we investigated its function in cell regulation chemoresistance in chemoresistant colorectal cancer cell lines. <h4>Methods: </h4>: Microarray, quantitative polymerase chain reaction (qRT-PCR) and westernblot were used to analysis the level of miR-100-5p. Th...

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Literature Corpus work
8e442b27-d73e-5c72-9d77-e8ca563e8c9e
DOI
10.21203/rs.3.rs-1360100/v1
Open publication

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miR-100-5p Enhanced Cell Cycle-mediated Chemoresistance Through Modulating CTDSPL/pRB/E2F1 Signaling Pathway in Oxaliplatin-Resistant Colorectal CancerDOI 10.21203/rs.3.rs-1360100/v1
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