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Beyond the Billion: Dose-Response Immunophenotyping and Machine Learning Classification of Live versus Heat-Treated Gram-Positive Probiotic Strains in Human Peripheral Blood Mononuclear Cells

2026-05-26

Abstract excerpt

<h4>ABSTRACT</h4> Probiotic research is constrained by three pervasive yet insufficiently challenged assumptions: the requirement for a minimum of one billion colony-forming units for efficacy, the necessity for gut colonization, and the inherent superiority of live over heat-treated preparations. This study addresses these gaps through a fully factorial experimental design evaluating ten Gram-positive probiotic...

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Literature Corpus work
8e3c3d57-35a9-55cd-b3af-8e622d0b6d69
DOI
10.64898/2026.05.26.727599
Open publication

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Beyond the Billion: Dose-Response Immunophenotyping and Machine Learning Classification of Live versus Heat-Treated Gram-Positive Probiotic Strains in Human Peripheral Blood Mononuclear CellsDOI 10.64898/2026.05.26.727599
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