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Optimal transport modeling uncovers spatial domain dynamics in spatiotemporal transcriptomics studies

2025-10-06

Abstract excerpt

Spatiotemporal transcriptomics is an emerging and powerful approach that adds a temporal dimension to spatial transcriptomics, enabling the characterization of dynamic changes in tissue architecture during development or disease progression. Here, we present SpaDOT ( Spa tial Do main T ransition detection), a computational method designed to identify spatial domains and infer their temporal dynamics across time...

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Literature Corpus work
8e2c1781-a59b-5a5a-a79d-5bca5820c0a8
DOI
10.1101/2025.10.06.680672
Open publication

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Optimal transport modeling uncovers spatial domain dynamics in spatiotemporal transcriptomics studiesDOI 10.1101/2025.10.06.680672
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