Article

Mapping disease traits onto spatiotemporal domain landscapes through scalable multi-sample integration of spatial transcriptomics

2025-12-17

Abstract excerpt

High-resolution spatial transcriptomics (ST) is generating massive datasets involving multiple tissue sections, continuous developmental stages, or various disease conditions. Yet, their scale, biological heterogeneity, and substantial batch effects hinder data integration for further analysis, particularly the temporal interpretation of disease-associated spatial domains within tissue organization landscapes. Her...

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Literature Corpus work: 29b9fe4b-5519-5f73-b845-564b52f0d8f8
DOI: 10.64898/2025.12.15.694341

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