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Article

Review: molecular genetics and pathology of hereditary small vessel diseases of the brain.

Neuropathology and applied neurobiology - 1 Feb 2011

Yamamoto Y, Craggs L, Baumann M, Kalimo H, Kalaria R N

Abstract excerpt

Advances in molecular genetics have enabled identification of several monogenic conditions involving small vessels predisposing to ischaemic and haemorrhagic strokes and diffuse white matter disease. With emphasis on cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), we review the molecular pathogenesis of recently characterized disorders including cerebral...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21062344
DOI: 10.1111/j.1365-2990.2010.01147.x

Genes

HTRA1
NOTCH3
TREX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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