HSV-1 Amplicon Vectors—Simplicity and Versatility

Abstract excerpt

A large number of viral vector systems, including those based on herpes simplex virus type 1 (HSV-1), retrovirus, adenovirus, and adeno-associated virus (AAV), have been developed over the past two decades. Reducing or eliminating toxic components, while conserving the efficiency of gene transfer, has been the primary goal of these efforts. All currently available vector systems have their advantages and...