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Article

A Novel Affordable and Reliable Framework for Accurate Detection and Comprehensive Analysis of Somatic Mutations in Cancer.

International journal of molecular sciences - 24 Jul 2024

Atzeni Rossano, Massidda Matteo, Pieroni Enrico, Rallo Vincenzo, Pisu Massimo, Angius Andrea

Abstract excerpt

Accurate detection and analysis of somatic variants in cancer involve multiple third-party tools with complex dependencies and configurations, leading to laborious, error-prone, and time-consuming data conversions. This approach lacks accuracy, reproducibility, and portability, limiting clinical application. Musta was developed to address these issues as an end-to-end pipeline for detecting, classifying, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39125613
DOI: 10.3390/ijms25158044
PMCID: PMC11311285

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