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Meta-analysis of the uncultured gut microbiome across 11,115 global metagenomes reveals a new candidate biomarker of health

2025-09-09

Abstract excerpt

The human gut microbiome plays an important biological role in host health, yet over 60% of gut species remain uncultured and hence inaccessible to experimental manipulation. Here we analysed 11,115 human gut metagenomes from 39 countries, 13 noncommunicable diseases and healthy individuals to understand the clinical relevance of the uncultured microbiome worldwide. We identified 317 uncultured species linked to d...

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Literature Corpus work
d537a477-06b1-5735-b32c-4d3c30e3beb0
DOI
10.1101/2025.09.09.675081
Open publication

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Meta-analysis of the uncultured gut microbiome across 11,115 global metagenomes reveals a new candidate biomarker of healthDOI 10.1101/2025.09.09.675081
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