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Expanded gut microbial genomes from Chinese populations reveal population-specific genomic features related to human physiological traits

31 Oct 2025

Abstract excerpt

BACKGROUND: A comprehensive and representative reference database is crucial for accurate taxonomic and functional profiling of the human gut microbiome in population-level studies. However, as approximately 70% of current microbial reference data originate from European and North American populations, other regions, including East Asia-and particularly China-remain significantly underrepresented. METHODS: We...

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PMID: 41174806
DOI: 10.1186/s13073-025-01566-x

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