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Rapid and wash-free anti-drug antibody assay enabled by the complementary nanoluciferase biosensor

2025-02-19

Abstract excerpt

Biotherapeutics have demonstrated remarkable therapeutic efficacy across a wide range of diseases; however, their clinical application is often hindered by the development of anti-drug antibodies (ADAs). Traditionally, ADA monitoring has relied on ligand-binding assays (LBAs) such as enzyme-linked immunosorbent assays (ELISA) or electrochemiluminescence assays (ECLIA). Although effective, these methods require mul...

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Literature Corpus work
8ce763dc-2db4-5df1-bfe9-29291809d4e8
DOI
10.1101/2025.02.14.638302
Open publication

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Rapid and wash-free anti-drug antibody assay enabled by the complementary nanoluciferase biosensorDOI 10.1101/2025.02.14.638302
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