Article

Escort-like somatic cells mediate early mouse fetal ovarian development but surface-derived Lgr5+ cells support primordial follicles

2019-11-26

Abstract excerpt

Ovarian murine somatic cells are essential to form first wave medullar follicles and second wave primordial follicles. Using single cell RNA sequencing we characterized the transcriptomes of both somatic and germline ovarian cells during fetal and early neonatal development. Wnt4-expressing somatic cells we term “escort-like cells (ELCs)” interact with incoming germ cells and early developing cysts of both sexes....

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Literature Corpus work: 7b63079e-374d-59fb-b6c6-4bb59998e172
DOI: 10.1101/855346

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