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Article

Preferential skeletal muscle myosin loss in response to mechanical silencing in a novel rat intensive care unit model: underlying mechanisms.

The Journal of physiology - 15 Apr 2011

Ochala Julien, Gustafson Ann-Marie, Diez Monica Llano, Renaud Guillaume, Li Meishan, Aare Sudhakar, Qaisar Rizwan, Banduseela Varuna C, Hedström Yvette, Tang Xiaorui, Dworkin Barry, Ford G Charles, Nair K Sreekumaran, Perera Sue, Gautel Mathias, Larsson Lars

Abstract excerpt

The muscle wasting and impaired muscle function in critically ill intensive care unit (ICU) patients delay recovery from the primary disease, and have debilitating consequences that can persist for years after hospital discharge. It is likely that, in addition to pernicious effects of the primary disease, the basic life support procedures of long-term ICU treatment contribute directly to the progressive...

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Identifiers

PMID: 21320889
DOI: 10.1113/jphysiol.2010.202044
PMCID: PMC3090600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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