Article

Escape from antimicrobial CRISPR-Cas9 in <i>E. coli</i> ST131 depends on the genetic context of the target gene

2025-08-06

Abstract excerpt

<h4>ABSTRACT</h4> Escherichia coli ( E. coli ) is a common bacterium in the human gut and an important cause of intestinal and extraintestinal infections. Some E. coli sequence types (ST) are associated with high pathogenicity. The Extraintestinal Pathogenic E. coli (ExPEC) ST131 is a globally distributed multidrug-resistant human pathogen associated with urinary tract and bloodstream infections. Antibiotic-re...

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Literature Corpus work: 8c541280-b5f7-565b-bb73-0860a7abde8b
DOI: 10.1101/2025.08.04.668416

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