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Article

Bacterial resistance to CRISPR-Cas antimicrobials.

Scientific reports - 26 Aug 2021

Uribe Ruben V, Rathmer Christin, Jahn Leonie Johanna, Ellabaan Mostafa Mostafa Hashim, Li Simone S, Sommer Morten Otto Alexander

Abstract excerpt

In the age of antibiotic resistance and precise microbiome engineering, CRISPR-Cas antimicrobials promise to have a substantial impact on the way we treat diseases in the future. However, the efficacy of these antimicrobials and their mechanisms of resistance remain to be elucidated. We systematically investigated how a target E. coli strain can escape killing by episomally-encoded CRISPR-Cas9 antimicrobials....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34446818
DOI: 10.1038/s41598-021-96735-4
PMCID: PMC8390487

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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