Article

Widespread Mitochondrial DNA Methylation Drift Contributes to Postoperative Delirium in Young and Old Mice

2020-10-02

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Mitochondrial dysfunction is linked to the etiopathogenesis of postoperative delirium (POD), which severely affects the prognosis of elderly patients undergoing surgery. The methylation of mitochondrial DNA (mtDNA), a new and incompletely described phenomenon that regulates the structure and function of mitochondria, is associated with aging. However, the relati...

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Literature Corpus work: 8c1606e6-382e-5ede-91af-515f2bcbf667
DOI: 10.21203/rs.3.rs-84137/v1

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