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Article

Mitochondrial DNA methylation drift and postoperative delirium in mice

1 Nov 2021

Abstract excerpt

BACKGROUND: Mitochondrial dysfunction is linked to the etiopathogenesis of postoperative delirium (POD), which severely affects the prognosis of elderly patients undergoing surgery. The methylation of mitochondrial DNA (mtDNA), a new and incompletely described phenomenon that regulates the structure and function of mitochondria, is associated with ageing. However, the relationship between mtDNA methylation and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34726198
DOI: 10.1097/eja.0000000000001620

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