Article

Conserved Function of Drg GTPases in Promoting Protein Synthesis in Stalled Ribosomes

2024-04-21

Abstract excerpt

Maintaining proper protein homeostasis is essential for cell physiology. The ribosome and GTPases, which are two of the most ancient and critical cellular molecules, are central players in protein synthesis and its regulation. Here we report the discovery of a new general translation factor that targets stalled ribosomes and promotes protein synthesis in an evolutionarily conserved manner. We show that the essenti...

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Literature Corpus work: 8bdd0348-5b03-59b2-8d8e-526b37f3a23d
DOI: 10.1101/2024.04.20.590341

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