Article

Concordance and dissonance: A genome-wide analysis of self-declared versus inferred ancestry in 10,250 participants from the HostSeq cohort

2025-06-13

Abstract excerpt

Accurate characterization of human diversity is foundational to equitable genomics. In this study, we analyzed self-declared and genome-derived ancestry in 10,250 participants from the pan-Canadian HostSeq cohort. Using the alignment-free ntRoot algorithm on whole genome sequencing data, we inferred global and local ancestry at the continental super-population level and compared these with self-reported sociocultu...

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Literature Corpus work: 8b9881b6-9a27-5cf9-9bd3-58b5874e7f61
DOI: 10.1101/2025.06.10.658783

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