Article

Functional and structural pathologies in skeletal muscle of a rat model of Duchenne muscular dystrophy

2025-09-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Duchenne muscular dystrophy (DMD) is a lethal pediatric degenerative muscle disease for which there is no cure. Robust preclinical models that recapitulate major clinical features of DMD are required to investigate efficacy of potential DMD therapeutics. Rat models of DMD have emerged as promising small animal models to accomplish this; however, there have been no comprehens...

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Literature Corpus work: 8b4cf84a-11e7-590e-b9bb-a4407c182ca0
DOI: 10.1101/2025.09.11.675592

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