Back to search

Article

­­­­GMP-conform production of [ 68Ga ]Ga-NeoB for positron emission tomography imaging of patients with gastrointestinal stromal tumor

2021-05-06

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>[<sup>68</sup>Ga]Ga-NeoB<sup> </sup>is a novel DOTA-coupled Gastrin Releasing Peptide Receptor (GRPR) antagonist with high affinity for GRPR and good in vivo stability. This study aimed at (1) the translation of preclinical results to the clinics and establish the preparation of [<sup>68</sup>Ga]Ga-NeoB<sup> </sup>using a GMP conform kit approach and a licensed...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
8af44b39-f479-5f51-9df2-4431b386902b
DOI
10.21203/rs.3.rs-446161/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
­­­­GMP-conform production of [ 68Ga ]Ga-NeoB for positron emission tomography imaging of patients with gastrointestinal stromal tumorDOI 10.21203/rs.3.rs-446161/v1
Multi-Curie Production of Gallium-68 on a Biomedical Cyclotron and Automated Radiolabelling of PSMA-11 and DOTATATESemantic proximity
Multi-curie Production of Gallium-68 on a Biomedical Cyclotron and Automated Radiolabelling of PSMA-11 and DOTATATESemantic proximity
Fully Automated Production of [68Ga]FAPI-46 with Gallium-68 from Cyclotron Using Liquid TargetsSemantic proximity
Optimized, automated and cGMP-compliant synthesis of the HER2 targeting [68Ga]Ga-ABY-025 tracerSemantic proximity
High‑yield, standardised automated radiosynthesis process for routine clinical insulinoma PET with [⁶⁸Ga]Ga‑NODAGA‑exendin‑4Semantic proximity
Semi-automated [68Ga]Ga-FAPI-46 radiosynthesis using GalliAd® generator and MiniAIO® synthesizer: development and validation for PET imaging of fibroblast activation proteinSemantic proximity
Effect of the Versatile Bifunctional Chelator AAZTA5 on the Radiometal Labelling properties and the in vitro performance of a Gastrin Releasing Peptide Receptor AntagonistSemantic proximity
Development of Integrin α5β1-targeted PET/NIR imaging probes for glioblastoma intraoperative navigation and intracavity targeted radionuclide therapySemantic proximity
Cyclotron-based production of 68Ga, [68Ga]GaCl3, and [68Ga]Ga-PSMA-11 from a liquid targetSemantic proximity
Profiling proteomic responses in small intestinal neuroendocrine tumor GOT1 after [177Lu]Lu-DOTATATE therapySemantic proximity
Identification of Genes Related to 68Ga-DOTATATE Organ Distribution in Homo SapiensSemantic proximity
Feasibility and Safety of 68Ga-PSMA-11 PET/CT Using Cyclotron-Produced 68Ga in Patients with Prostate CancerSemantic proximity
Select a neighboring publication to make it the new centre.