Article

Discovery of new antibacterial accramycins from a genetic variant of the soil bacterium, <i>Streptomyces</i> sp. MA37

2020-09-14

Abstract excerpt

Continued mining of natural products from the strain Streptomyces sp. MA37 in our laboratory led to the discovery of a minor specialised metabolite (SM) called accramycin A. Owing to its low yield (0.2mg/L) in the wild type strain, we investigated the roles of regulatory genes in the corresponding biosynthetic gene cluster ( acc BGC) through gene inactivation with the aim of improving the titre of this compound....

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Literature Corpus work: 8a830f50-3ced-5e13-b403-2191b6c3ba1e
DOI: 10.1101/2020.09.14.295873

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Discovery of new antibacterial accramycins from a genetic variant of the soil bacterium, <i>Streptomyces</i> sp. MA37DOI 10.1101/2020.09.14.295873Read

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