Article

Actinomycin analogs from soil-derived Streptomyces sp. PSU-S4-23 with activity against MRSA

2025-11-03

Abstract excerpt

<title>Abstract</title> <p> Genome-based discovery provides a powerful approach for identifying bioactive natural products. Using this approach, we identified actinomycin production in <italic>Streptomyces</italic> sp. PSU-S4-23. The genome contains a nonribosomal peptide synthetase (NRPS) biosynthetic gene cluster closely matching the actinomycin D reference (BGC0000296), including two NRPS genes encoding the...

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Literature Corpus work: ef503d85-eec2-5bd7-b66c-0b271c538801
DOI: 10.21203/rs.3.rs-7993493/v1

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